About 24 results found for searched term "Arachidonic acid" (0.145 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9227 | Arachidonic acid | Metabolite/Endogenous Metabolite |
| Immunocytophyte | ||
| Arachidonic acid (AA) is an unsaturated ω6 fatty acid constituent of the phospholipids of cell membranes. | ||
| M9339 | Methyl arachidonate | Others |
| Arachidonic Acid methyl ester | ||
| Methyl arachidonate is the keystone essential fatty acid at the origin of the arachidonic acid cascade. | ||
| M21846 | 5,6-dehydro Arachidonic Acid | Others |
| 5,6-dehydro AA | ||
| 5,6-dehydro Arachidonic Acid | ||
| M3400 | Idebenone | Ferroptosis |
| CV-2619 | ||
| Idebenone, a mitochondrial protector, has neuroprotective properties and can be used to study Alzheimer's disease, Huntington's disease, and can cross the blood-brain barrier. Idebenone (oxidized form) inhibited arachidonic acid enzyme metabolism in astrocyte homogenates (IC50=16.65 μM). Idebenone is a coenzyme Q10 analogue and antioxidant that induces apoptosis (apoptotic) in human dopaminergic neuroblastoma SHSY-5Y cells. | ||
| M4764 | taraxasteryl-acetate | Others |
| Taraxasteryl acetate was isolated from sagittal plasmodium and showed a broad spectrum of anti-inflammatory activity. Taraxasteryl acetate can reduce posterior claw edema induced by dextran, yeast glycan and arachidonic acid in rats. Taraxasteryl acetate can be used to study local inflammation. | ||
| M5573 | Diethylcarbamazine citrate | Parasite |
| Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria; is highly specific for several parasites and does not contain any toxic metallic elements. | ||
| M7711 | Cloricromene | Others |
| Antithrombotic coumarin derivative that inhibits platelet and leukocyte function and suppresses arachidonic acid liberation by interfering with PLA2 activation. | ||
| M9568 | SC-26196 | Others |
| SC26196 | ||
| SC-26196 is a potent, orally active D6D inhibitor (IC50 = 0.2 µM in a rat liver microsomal assay) that completely blocks the conversion of linoleic acid to arachidonic acid (AA). | ||
| M19214 | Rotundatin | Others |
| Rotundatin is useful in inhibition of the aggregation of platelets induced by arachidonic acid and collagen. | ||
| M22519 | Prostaglandin A2 | Metabolite/Endogenous Metabolite |
| PGA2; Medullin | ||
| Prostaglandin A2 (PGA2) is a endogenous metabolite derived from arachidonic acid, it plays a vital role in the induction of apoptosis. Prostaglandin A2 blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase. Prostaglandin A2 induces p53-dependent apoptosis. | ||
| M27952 | L-670596 | Prostaglandin Receptor |
| L-670596 is an orally active and selective thrombsxane A2 receptor/prostaglandin receptor antagonist. L-670596 inhibits arachidonic acid and U-44069 induced bronchoconstriction in the guinea pig. L-670596 also inhibits the aggregation of human platelet rich plasma induced by U-44069. | ||
| M29503 | LEI110 | Others |
| LEI110 is a potent, selective and cell-permeable pan-inhibitor of the HRASLS family of thiol hydrolases. LEI110 inhibits PLA2G16, HRASLS2, RARRES3 and iNAT, with pIC50 values of 7.0, 6.8, 6.8, and 7.6, respectively. LEI110 reduces cellular arachidonic acid levels and oleic acid-induced lipolysis in HepG2 cells. | ||
| M31179 | 12-HETE | Apoptosis |
| 12-HETE is a metabolite of arachidonic acid catalyzed by lipoxygenase (12-LOX). It is also a highly selective ligand that can be used to label mu opioid receptors in membrane and tissue sections. In addition, 12-HETE functions as an inhibitor of apoptosis. | ||
| M31252 | 8,11,14-Eicosatriynoic acid | Others |
| 8,11,14-Eicosatriynoic Acid, as an inhibitor of prostaglandin, leukotriene biosynthesis, and arachidonic acid-induced platelet aggregation, blocks human 12-lipoxygenase (12-LO), cyclooxygenase (COX)and 5-lipoxygenase (5-LO) with IC50 values of 0.46 μM, 14 μMand 25 μM, respectively. | ||
| M38966 | Saikogenin D | Prostaglandin Receptor |
| Saikogenin D activates epoxygenases that converts arachidonic acid to epoxyeicosanoids and dihydroxyeicosatrienoic acids, and the metabolites secondarily inhibit prostaglandin E2 (PGE2) production. Saikogenin D results in an elevation of [Ca2+]i due to Ca2+ release from intracellular stores. | ||
| M39844 | Aristolactam A IIIa | DYRK |
| Aristolactam A IIIa (Sch 546909) is a DYRK1A Inhibitor. Aristolactam A IIIa inhibits platelet aggregation induced by arachidonic acid (AA), collagen and platelet-activating factor (PAF). Aristolactam A IIIa has strong cytotoxic effect on HeLa cells. | ||
| M40037 | Piperlotine C | Others |
| Piperlotine C is an alkaloid isolated from Piper lolot, with anti-platelet aggregation induced by arachidonic acid, and the IC50 is 26.6 µg/mL. | ||
| M40145 | Kaempferol 3-O-(2'',4''-di-acetyl-3''-cis-p-coumaroyl-6''-trans-p-coumaroyl)-β-D-glucopyranoside | Others |
| Kaempferol 3-O-(2'',4''-di-acetyl-3''-cis-p-coumaroyl-6''-trans-p-coumaroyl)-β-D-glucopyranoside suppresses the superoxide generation induced by arachidonic acid. | ||
| M40333 | Piperlotine D | Others |
| Piperlotine D is an antiplatelet aggregation agent. Piperlotine D can be extracted from Piper lolot with antiplatelet aggregation activity. Piperlotine D inhibits arachidonic acid-induced platelet aggregation with an IC50 of 43.4 μg/mL. | ||
| M45337 | ALOX15-IN-2 | Lipoxygenase |
| ALOX15-IN-2 is a potent inhibitor of rabbit and human ALOX15 linoleate oxygenase activity, with IC50s of 1.55 and 2.79 μM for linoleic acid (LA) and arachidonic acid (AA), the immediate homologs of ALOX15, respectively. | ||
| M52550 | Phospholipase A2 | Phospholipase |
| Phospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (AA). | ||
| M56557 | RU-TRAAK-2 | Potassium Channel |
| RU-TRAAK-2 is a completely reversible TRAAK (TWIK-related arachidonic acid-stimulated K+ channel) inhibitor. | ||
| M56352 | PPOH | COX |
| PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. | ||
| M56336 | 15(S)-HPETE | Others |
| 15(S)-HPETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. | ||
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