About 2 results found for searched term "Aminopterin" (0.139 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9787 | Aminopterin | Antifolate |
| 4-Aminofolic acid | ||
| Aminopterin is a folic acid derivative used as a rodenticide that has been shown to be teratogenic, and a dihydrofolate reductase inhibitor used to treat rheumatoid arthritis and leukemia. | ||
| M27833 | Talotrexin | Antifolate |
| PT523 | ||
| Talotrexin (PT523), an analog of Aminopterin, is a nonpolyglutamatable classic antifolate. Talotrexin is a RFC (reduced folate carrier) specific inhibitor and selectively inhibits RFC transport. Talotrexin shows antitumor activity by targeting DHFR to inhibit tumor growth. | ||
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