Actinomycin X2 - Search Results

About 3 results found for searched term "Actinomycin X2" (0.217 seconds)

Cat.No.	Name	Target
M53848	Actinomycin X2	Antibiotic
	Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL.
M8641	LP117	Others
	LP117 is a pirinixic acid derivative that interferes with ATP-binding cassette (ABC) transporter ABCB1-mediated substrates transport, including vincristine, vinorelbine, paclitaxel, and actinomycin D, but not doxorubicin, rhodamine 123, or JC-1.
M4881	Actinomycin D	DNA/RNA Synthesis
	Actinomycin Aiv; Dactinomycin; Act D; RASP-101
	Actinomycin D (Dactinomycin) is an antibiotic found in Streptomyces microsporum with antibacterial and anti-tumor effects. Actinomycin D is an inhibitor of RNA and protein synthesis. Actinomycin D can inhibit the protein synthesis of bacteria, directly bind to the guanine groups of single-stranded or double-stranded DNA in the transcriptional initiation complex, inhibit the activity of DNA-dependent RNA polymerase, and interfere with the transcription process of DNA, thereby inhibiting mRNA synthesis. Actinomycin D inhibits DNA repair with an IC50 value of 0.42 μM.