About 1 result found for searched term "AZ12601011 " (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M57237 | AZ12601011 | TGF-β Receptor |
| AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor with an IC50 of 18 nM and a Kd of 2.9 nM. AZ12601011 inhibits phosphorylation of SMAD2 via selectively inhibiting ALK4, TGFBR1, and ALK7. AZ12601011 inhibits mammary tumor growth. | ||
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