About 12 results found for searched term "AZ-67" (0.056 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1897 | AZD6765 | GluR |
| AZD6765 is an NMDA receptor antagonist. | ||
| M2197 | Sulfasalazine | Ferroptosis |
| Salazopyrin; Azulfidine; Sulphasalazine; SAS; NSC 667219 | ||
| Sulfasalazine is a sulfonamide agent derived from Mesalazine. Sulfasalazine has xC-system inhibitory activity associated with iron death and is primarily used as an anti-inflammatory agent. Sulfasalazine can suppress NF-κB activity. Sulfasalazine is a type 1 ferroptosis inducer. | ||
| M4854 | BMN-673 8R,9S | PARP |
| Talazoparib (8R,9S); (8R,9S)-LT-673 | ||
| BMN-673 (8R,9S) is the (8R,9S) enantiomer of BMN-673.BMN673 is a potent inhibitor of poly (ADP-ribose) polymerases (PARP)-1 and -2. | ||
| M8914 | Ceralasertib (AZD6738) | ATM/ATR |
| Ceralasertib (AZD6738) is an orally active, selective ATR kinase inhibitor with an IC50 of 1 nM. AZD6738 inhibits ATR kinase activity and impels cell viability. AZD6738 induces rapid cell death in tumor cells with an ATM gene defect. | ||
| M13973 | AZD9567 | GCR |
| Mizacorat | ||
| AZD9567 (Mizacorat) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation. | ||
| M28820 | AZ-PFKFB3-67 | PFKFB3 |
| AZ-PFKFB3-67 is potent and selective metabolic kinase PFKFB3 inhibitor, with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively. | ||
| M29932 | AZ10397767 | CXCR |
| AZ10397767 is an orally active, selective CXCR2 receptor antagonist with an IC50 of 1 nM. AZ10397767 attenuates the Oxaliplatin-induced NF-κB transcriptional activity and potentiates Oxaliplatin-induced apoptosis in androgen-independent prostate cancer (AIPC) cells. AZ10397767 significantly inhibits neutrophil recruitment into tumors which then adversely affects tumor growth in vitro and in vivo. | ||
| M31070 | AZ-PFKFB3-67 quarterhydrate | PFKFB3 |
| AZ-PFKFB3-67 quarterhydrate is potent and selective metabolic kinase PFKFB3 inhibitor, with IC50s of 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively. | ||
| M31413 | AZ-67 | PFKFB3 |
| AZ-67 is an inhibitor of PFKFB3 as well as glycolysis and can be used in studies related to neurodegenerative diseases. | ||
| M56340 | AZD-5672 | CCR |
| AZD-5672 is an orally active, potent, and selective CCR5 antagonist (IC50=0.32 nM). | ||
| M56314 | AZ12672857 | Prostaglandin Receptor |
| AZ12672857 is an orally active inhibitor of EphB4 (IC50=1.3 nM) and Src kinases. | ||
| M56161 | AZD-1678 | CCR |
| AZD-1678 is a potent CCR4 receptor antagonist, with a pIC50 of 8.6. | ||
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