About 9 results found for searched term "AZ-33" (0.061 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1662 | AZD8330 | MEK |
| ARRY-424704, ARRY-704 | ||
| AZD8330 (ARRY-424704) is a novel, selective, highly efficacious, uncompetitive MEK inhibitor with an IC50 of 7 nM. | ||
| M1587 | Hydroxy Itraconazole | Antibiotic |
| Hydroxy Itraconazole; R-63373 | ||
| Itraconazole metabolite Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent. | ||
| M6478 | AZ Dyrk1B 33 | Others |
| AZ Dyrk1B 33 is a potent and selective Dyrk1B kinase inhibitor. | ||
| M9784 | Naloxegol oxalate | Opioid Receptor |
| NKTR-118 oxalate; AZ-13337019 oxalate | ||
| Naloxegol oxalate (NKTR-118 oxalate; AZ-13337019 oxalate) is a peripherally-selective opioid antagonist for the treatment of opioid-induced constipation. | ||
| M9849 | AZ-33 | LDH |
| AZ33; LDHA Inhibitor 33 | ||
| AZ-33 is a potent lactate dehydrogenase A (LDHA) inhibitor with IC50 of 0.5 μM. | ||
| M11267 | Camizestrant | Estrogen Receptor |
| AZD-9833 | ||
| Camizestrant (AZD-9833) is an effective oral antagonist of the active estrogen receptor (ER). Camizestrant can be used in the study of ER+ HER2- breast cancer. | ||
| M29109 | AZ13705339 | PAK |
| AZ13705339 is a highly potent and selective PAK1 inhibitor with IC50s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 has binding affinities to PAK1 and PAK2, with Kds of 0.28 nM and 0.32 nM, respectively. AZ13705339 can be used in the research of cancers. | ||
| M31006 | AZ13705339 hemihydrate | PAK |
| AZ13705339 hemihydrate is a highly potent and selective PAK1 inhibitor with IC50s of 0.33 nM and 59 nM for PAK1 and pPAK1, respectively. AZ13705339 hemihydrate has binding affinities to PAK1 and PAK2, with Kds of 0.28 nM and 0.32 nM, respectively. AZ13705339 hemihydrate can be used in the research of cancers. | ||
| M45125 | AZD-8233 | PCSK9 |
| AZD-8233 is an orally active, antisense oligonucleotide (ASO) targeting PCSK9 that targets and inhibits the translation and protein synthesis of PCSK9 mRNA in hepatocytes and reduces circulating LDL-C levels. It can be used in studies related to hypercholesterolemia. | ||
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