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About 11 results found for searched term "AZ-23" (0.036 seconds)
| Cat.No. | Name | Information |
|---|---|---|
| M1657 | Atazanavir Sulfate | Atazanavir sulfate (BMS-232632, Reyataz) is an azapeptide inhibitor of HIV-1 protease. |
| M2422 | AZD5423 | AZD5423 is a novel nonsteroidal glucocorticoid receptor agonist. |
| M2437 | Bazedoxifene hydrochloride | Bazedoxifene hydrochloride is a novel, non-steroidal, indole-based estrogen receptor modulator (SERM) binding to both ERα and ERβ with IC50 of 23 nM and 89 nM. |
| M5427 | Atazanavir | Atazanavir is an azapeptide and HIV-protease inhibitor that is used in the treatment of HIV infections and AIDS in combination with other anti-HIV agents. |
| M10143 | AZ3451 | AZ3451 is a potent PAR2 (protease-activated receptor-2) antagonist with IC50 of 23 nM, which plays a part in inflammation response, apoptosis, autophagy and cellular senescence during Osteoarthritis (OA). |
| M10339 | Fexinidazole | Fexinidazole (also known as Hoe-239) is an orally active, potent antiparasitic agent. |
| M10372 | Vazegepant hydrochloride | Vazegepant (BHV-3500) hydrochloride is a highly affinity CGRP receptor antagonist (hCGRP Ki= 0.023 nM). |
| M11173 | PC945 | PC945 is a potent antifungal triazole drug that is resistant to a variety of sensitive and resistant strains of Aspergillus fumigatus. PC945 is a potent, tightly bound inhibitor of aspergilloxine 14α-demethylase (CYP51A/CYP51B) activity.IC50s are 0.23 μM and 0.22 μM, respectively. |
| M14265 | Pantoprazole sodium hydrate | Pantoprazole sodium hydrate (BY10232 sodium hydrate) is an orally active and potent proton pump inhibitor (PPI). |
| M14579 | AZ-23 | AZ-23 is an ATP-competitive and orally bioavailable Trk kinase A/B/C inhibitor with IC50s of 2 nM (TrkA), 8 nM (TrkB), 24 nM (FGFR1), 52 nM (Flt3), 55 nM (Ret), 84 nM (MuSk), 99 nM (Lck), respectively. |
| M20398 | Ixazomib Citrate (MLN9708) | Ixazomib Citrate (MLN9708) immediately hydrolyzed to MLN2238, the biologically active form, on exposure to aqueous solutions or plasma. MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50/Ki of 3.4 nM/0.93 nM in cell-free assays, less potent to β1 and little activity to β2. Phase 3. |
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