About 6 results found for searched term "AZ-23" (0.05 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2422 | AZD5423 | GCR |
| AZD5423 is a novel nonsteroidal glucocorticoid receptor agonist. | ||
| M14579 | AZ-23 | Trk |
| AZ23; AZ 23 | ||
| AZ-23 is an ATP-competitive and orally bioavailable Trk kinase A/B/C inhibitor with IC50s of 2 nM (TrkA), 8 nM (TrkB), 24 nM (FGFR1), 52 nM (Flt3), 55 nM (Ret), 84 nM (MuSk), 99 nM (Lck), respectively. | ||
| M25432 | NAZ2329 | Phosphatase |
| NAZ2329 is the first cell-permeable inhibitor of R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs), allosterically and preferentially inhibits PTPRZ (IC50=7.5 µM for hPTPRZ1) and PTPRG (IC50=4.8 µM for hPTPRG) over other PTPs. | ||
| M45125 | AZD-8233 | PCSK9 |
| AZD-8233 is an orally active, antisense oligonucleotide (ASO) targeting PCSK9 that targets and inhibits the translation and protein synthesis of PCSK9 mRNA in hepatocytes and reduces circulating LDL-C levels. It can be used in studies related to hypercholesterolemia. | ||
| M56162 | AZD2423 | CCR |
| AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator. | ||
| M57978 | AZD-1236 | Others |
| AZD-1236 | ||
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