About 8 results found for searched term "AT 1001" (0.496 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M58539 | AT 1001 | AChR/AChE |
| AT1001 | ||
| AT 1001 is a high-affinity and selective antagonist of the α3β4 nicotinic acetylcholine receptor (α3β4 nAChR) with Ki of 2.64 nM. | ||
| M10370 | Larazotide acetate | Others |
| AT-1001 | ||
| Larazotide acetate also known as AT-1001, is a tight junction regulator and reverses leaky junctions to their normally closed state. Larazotide acetate is a peptide which is an orally active zonulin antagonist. Larazotide acetate shows antiviral activity to varicella-zoster virus (VZV) with EC50s of 44.14 and 59.06 μM for strain OKA and 07-1, respectively. | ||
| M10726 | ORY-1001 (trans) | Histone demethylase |
| ORY-1001 dihydrochloride; RG6016 dihydrochloride; RO 7051790 dihydrochloride | ||
| Dihydrochloride, Iadademstat (ORY-1001) is an irreversible inhibitor of selective Lysine-specific demethylase 1A (KDM1A/LSD1). | ||
| M11025 | M1001 | HIF |
| M1001 is a weaker HIF-2α agonist that binds directly to the HIF-2α PAS-B domain.Kd The value is 667 nM. The M1001 enhances stability between HIF-2α-ARNT complexes. | ||
| M27593 | JAMI1001A | GluR |
| JAMI1001A is a positive allosteric modulator of AMPA receptor. JAMI1001A efficaciously modulates AMPA receptor deactivation and desensitization of both flip and flop receptor isoforms. | ||
| M28513 | DPM-1001 | Phosphatase |
| DPM-1001 is a potent, specific, orally active and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC50 of 100 nM. DPM-1001 is an analog of the specific PTP1B inhibitor MSI-1436. DPM-1001 has anti-diabetic property. | ||
| M30397 | VU10010 | AChR/AChE |
| VU10010 is a potent, highly selective and allosteric M4 mAChR potentiator with an EC50 of 400 nM. VU10010 binds to an allosteric site on M4 mAChR and increases affinity for acetylcholine and coupling to G proteins. VU10010 increases carbachol-induced depression of transmission at excitatory but not inhibitory synapses in the hippocampus. | ||
| M31059 | DPM-1001 trihydrochloride | Phosphatase |
| DPM-1001 trihydrochloride is a potent, specific, orally active and non-competitive inhibitor of protein-tyrosine phosphatase (PTP1B) with an IC50 of 100 nM. DPM-1001 trihydrochloride is an analog of the specific PTP1B inhibitor MSI-1436. DPM-1001 trihydrochloride has anti-diabetic property. | ||
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