About 1 result found for searched term "ARN1468 " (0.138 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28296 | ARN1468 | Others |
| ARN1468 (compound 5) is an orally active and potent serpins inhibitor. ARN1468 can inhibit serpins activity would set the protease free to further reduce prion accumulation. ARN1468 shows anti-prion effect in ScGT1 RML, ScGT1 22L, ScN2a RML, and ScN2a 22L cell lines, with EC50 values of 8.64, 19.3, 11.2, and 6.27 μM. | ||
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