About 1 result found for searched term "ARN-21934 " (0.124 seconds)
Cat.No. | Name | Target |
---|---|---|
M29392 | ARN-21934 | Topoisomerase |
ARN-21934 is a potent, highly selective, blood-brain barrier (BBB) penetrant inhibitor for human topoisomerase II α over β. ARN-21934 inhibits DNA relaxation with an IC50 of 2 μM as compared to the anticancer agent Etoposide (IC50=120 μM). ARN-21934 exhibits a favorable in vivo pharmacokinetic profile and is a promising lead compound for anticancer research. |
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