About 8 results found for searched term "ARC12" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42777 | ARC12 | Others |
| ARC12 is a secondary metabolism probe that modulates the production of Streptomyces coelicolor secondary metabolites. | ||
| M2104 | BYL-719 | PI3K |
| Alpelisib; BYL719 | ||
| Alpelisib (Byl-719) is an effective, selective PI3Kα inhibitor with oral activity. Alpelisib (Byl-719) was targeted to PIK3CA mutated carcinoma. The IC50 of Alpelisib (Byl-719) against P110 α, P110 γ, p110δ and P110 β were 5 nM, 250 nM, 290 nM and 1200 nM, respectively. It has antitumor activity. | ||
| M15041 | Recombinant Human MEC/CCL28 (E. coli) | Cytokines and Growth Factors |
| Chemokine (C-C motif) ligand 28; CCL-28; SCYA28 | ||
| CCL28 (CC chemokine ligand 28), a novel CC chemokine, was identified by TBLASTN search using the human Genome System (HGS) and Genbank dbEst databases using a consistent sequence of human chemokines. Protein structure: CCL28 (Ser20-Tyr127), Accession # ：Q9NRJ3. | ||
| M28645 | Azilsartan mepixetil | Angiotensin Receptor |
| Azilsartan mepixetil is the antagonist of angiotensin II receptor. Azilsartan mepixetil has stronger and longer blood pressure effect, more abvious and longer lasting heart rate lowering effect and high safety. Azilsartan mepixetil achieves ideal protective effect for heart and kidney functions. Azilsartan mepixetil has the potential for the research of hypertension, chronic heart failure and diabetic nephropathy (extracted from patent CN107400122A). | ||
| M30731 | SLEC-11 | Others |
| SLEC-11 acts as a potential synthetic lethal lead for the research of gastric cancer. AL-GDa62 shows EC50 of 12.2 μM and 8.2 μM for isogenic mammary epithelial cells MCF10A-WT (wild-type) and MCF10A-CDH1-/-. | ||
| M38635 | 1,4,6-Trihydroxy-5-methoxy-7-prenylxanthone | Antibiotic |
| 1,4, 6-trihydroxy-5-methoxy-7-prenylxanthone is an antimicrobial agent that can be isolated from the genus garcinia. 1,4, 6-trihydroxy-5-methoxy-7-prenylxanthone inhibits S. aureus and B. cereus with MIC values of 128 μg/mL and 200 μg/mL, respectively. | ||
| M40247 | Garciniaxanthone E | Others |
| Garciniaxanthone E is a xanthone compound. Garciniaxanthone E significantly enhances cellular nerve growth factor (NGF)-mediated neurite outgrowth in PC12D cells. Garciniaxanthone E contributes to basic research and medicinal development in neurodegenerative diseases. | ||
| M41654 | SMD-3040 | PROTAC |
| SMD-3040 is a potent and selective of SMARCA2 PROTAC degrader (DC50: 12 nM). | ||
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