AM404 - Search Results | AbMole BioScience

About 5 results found for searched term "AM404" (0.129 seconds)

Cat.No.	Name	Target
M11426	AM404	Cannabinoid
	N-(4-HYDROXYPHENYL)-ARACHIDONYLAMIDE
	AM404 is an endocannabinoid reuptake inhibitor that can block anandamide transport with IC50 values in the low mole range. The isolated rat hepatic artery was constricted by norepinephrine and relaxed by AM404. PEC50 value was 7.4 (corresponding EC50 value was 0.04 µM). It has neuroprotective effects.
M25079	Zeluvalimab	PD-1/PD-L1
	AMG-404
	Zeluvalimab (AMG-404) is a monoclonal antibody targeting the PD-1 receptor that can be used for the research of cancer.
M58515	CDDO-TFEA	Keap1-Nrf2
	CDDO-Trifluoethyl amide; RTA 404; TP-500
	CDDO-TFEA (RTA 404; TP-500) is a trifluoroacetamide derivative of CDDO with enhanced ability to cross the blood-brain barrier. CDDO is an Nrf2 activator that inhibits proliferation and induces differentiation and apoptosis in various cancer cells. CDDO-TFEA can enhance Nrf2 expression and signaling in various neurodegenerative disease models.
M8335	NCX 4040	Apoptosis
	NCX4040; NO-Aspirin
	NCX4040 (NO-Aspirin) is a nitric oxide-donating form of aspirin, and a non-steroidal anti-inflammatory agent. NCX4040 induces apoptosis in PC3 metastatic prostate cancer cells.
M24942	Vibecotamab	Others
	XmAb14045
	Vibecotamab (XmAb14045) is a potent bispecific antibody against CD123 and CD3 that stimulates T cell-mediated targeted killing of CD123-expressing cells. Vibecotamab has antitumor activity and can be used in acute myeloid leukaemia studies.