About 7 results found for searched term "AG 99" (0.062 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1644 | AG-014699 phosphate | PARP |
| PF-01367338, Rucaparib phosphate | ||
| AG-014699 (PF-01367338, Rucaparib) is a PARP inhibitor with a Ki of 1.4 nM. | ||
| M4931 | Rucaparib | PARP |
| AG014699; PF-01367338 | ||
| Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1, also showing binding affinity to eight other PARP domains. | ||
| M6413 | AG 99 | Others |
| AG 99 is a eGFR-kinase inhibitor. | ||
| M24615 | Abicipar pegol | VEGFR/PDGFR |
| AGN-150998; MP0112 | ||
| Abicipar pegol (AGN-150998, MP0112) is an anti-VEGF DARPin molecule, a novel class of small proteins containing ankyrin repeat domains engineered to bind with high specificity and affinity to target proteins. Abicipar pegol effectively inhibits angiogenesis and vascular permeability and is used in the study of diseases related to ocular inflammation by intravitreal injection, reducing mean retinal thickness and leakage area. | ||
| M27718 | AUTEN-99 hydrobromide | Others |
| Autophagy enhancer-99 hydrobromide | ||
| AUTEN-99 (hydrobromide) is a novel inhibitor of the myotubularin phosphatase Jumpy (also called MTMR14). AUTEN-99 (hydrobromide) crosses the blood-brain barrier and exerts potent neuroprotective effects. | ||
| M29575 | AGI-41998 | Somatostatin Receptor |
| AGI-41998 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A). AGI-41998 is a brain-penetrant compound. AGI-41998 has the potential for exploring the effects of SAM modulation in the central nervous system (CNS) and research of cancer disease. | ||
| M56785 | AGN 196996 | RAR/RXR |
| AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM). | ||
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