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Abicipar pegol (AGN-150998, MP0112) is an anti-VEGF DARPin molecule, a novel class of small proteins containing ankyrin repeat domains engineered to bind with high specificity and affinity to target proteins. Abicipar pegol effectively inhibits angiogenesis and vascular permeability and is used in the study of diseases related to ocular inflammation by intravitreal injection, reducing mean retinal thickness and leakage area.
CAS Number | 1327278-94-3 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[3] Claudio Campa. Curr Drug Targets. New Anti-VEGF Drυgs in Ophthalmology
[4] Ashish Sharma, et al. Eye (Lond). Abicipar pegol: the non-monoclonal antibody anti-VEGF
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