Free shipping on all orders over $ 500

Abicipar pegol

Cat. No. M24615

All AbMole products are for research use only, cannot be used for human consumption.

Abicipar pegol Structure
Synonym:

AGN-150998; MP0112

Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Abicipar pegol (AGN-150998, MP0112) is an anti-VEGF DARPin molecule, a novel class of small proteins containing ankyrin repeat domains engineered to bind with high specificity and affinity to target proteins. Abicipar pegol effectively inhibits angiogenesis and vascular permeability and is used in the study of diseases related to ocular inflammation by intravitreal injection, reducing mean retinal thickness and leakage area.

Chemical Information
CAS Number 1327278-94-3
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Rehan M Hussain, et al. Expert Opin Biol Ther. Abicipar pegol for neovascular age-related macular degeneration

[2] Lorenzo Ferro Desideri, et al. Expert Opin Investig Drugs. Abicipar pegol: an investigational anti-VEGF agent for the treatment of wet age-related macular degeneration

[3] Claudio Campa. Curr Drug Targets. New Anti-VEGF Drυgs in Ophthalmology

[4] Ashish Sharma, et al. Eye (Lond). Abicipar pegol: the non-monoclonal antibody anti-VEGF

[5] Elad Moisseiev, et al. Eye (Lond). Abicipar pegol-a novel anti-VEGF therapy with a long duration of action

Related VEGFR/PDGFR Products
Isolinderalactone

Isolinderalactone suppresses human glioblastoma growth and angiogenic activity through the inhibition of VEGFR2 activation in endothelial cells. Isolinderalactone suppressed the expression of B-cell lymphoma 2 (BCL-2), as well as of survivin and X-linked inhibitor of apoptosis protein (XIAP).

Oglufanide

Oglufanide (H-Glu-Trp-OH) is a dipeptide immunomodulator isolated from calf thymus.

KLTWQELYQLKYKGI

KLTWQELYQLKYKGI (QK) is a VEGF mimicking peptide, binds to the VEGF receptors and competes with VEGF.

Protein LMWP

Protein LMWP is a cell-penetrating peptide with vascular endothelial growth factor (VEGF) inhibitory activity.

CBO-P11

CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis.

  Catalog
Abmole Inhibitor Catalog




Keywords: Abicipar pegol, AGN-150998; MP0112 supplier, VEGFR/PDGFR, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.