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Abicipar pegol

Cat. No. M24615

All AbMole products are for research use only, cannot be used for human consumption.

Abicipar pegol Structure

AGN-150998; MP0112

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Biological Activity

Abicipar pegol (AGN-150998, MP0112) is an anti-VEGF DARPin molecule, a novel class of small proteins containing ankyrin repeat domains engineered to bind with high specificity and affinity to target proteins. Abicipar pegol effectively inhibits angiogenesis and vascular permeability and is used in the study of diseases related to ocular inflammation by intravitreal injection, reducing mean retinal thickness and leakage area.

Chemical Information
CAS Number 1327278-94-3
Storage Please store the product under the recommended conditions in the Certificate of Analysis.

[1] Rehan M Hussain, et al. Expert Opin Biol Ther. Abicipar pegol for neovascular age-related macular degeneration

[2] Lorenzo Ferro Desideri, et al. Expert Opin Investig Drugs. Abicipar pegol: an investigational anti-VEGF agent for the treatment of wet age-related macular degeneration

[3] Claudio Campa. Curr Drug Targets. New Anti-VEGF Drυgs in Ophthalmology

[4] Ashish Sharma, et al. Eye (Lond). Abicipar pegol: the non-monoclonal antibody anti-VEGF

[5] Elad Moisseiev, et al. Eye (Lond). Abicipar pegol-a novel anti-VEGF therapy with a long duration of action

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Abmole Inhibitor Catalog

Keywords: Abicipar pegol, AGN-150998; MP0112 supplier, VEGFR/PDGFR, inhibitors, activators

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