About 9 results found for searched term "A 196" (0.058 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3184 | Resmetirom (MGL-3196) | Thyroid Hormone Receptor |
| VIA-3196; MGL-3196 | ||
| Resmetirom (MGL-3196, VIA-3196, resmetirom) is a potentially first-in-class, liver-targeted, orally active, selective thyroid hormone receptor (THR)-β agonist with an EC50 value of 0.21 μM. Resmetirom avoids the activation of THR-α receptors that mediate thyroid hormone activity outside of the liver, including the heart and bone. Resmetirom avoids the activation of THR-α receptors that mediate extrahepatic (including cardiac and skeletal) thyroid hormone activity and can be used in studies of non-alcoholic steatohepatitis (NASH). | ||
| M5306 | Acalabrutinib | BTK |
| ACP-196 | ||
| Acalabrutinib(ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway.BMX, and TEC, respectively) and no activity against EGFR. | ||
| M6362 | A 196 | Histone Methyltransferase |
| A-196 is a potent selective inhibitor of SUV420H1 and SUV420H2 with IC50 values of 25 nM and 144 nM, respectively, and biochemically inhibits SUV4-20 in a substrate-competitive manner. In addition, A-196 is a first-in-class chemical probe for SUV4-20, which can be used to study the role of histone methyltransferases in genome integrity. | ||
| M9230 | Indole-3-acetamide | Plant growth regulators |
| 3-Indolylacetamide; NSC 1969 | ||
| Indole-3-acetamide is an auxin precursor. | ||
| M20097 | WAY-321961 | Others |
| WAY-321961 is a Protein kinase d inhibitor | ||
| M20256 | TGFβ-IN-5 | TGF-beta/Smad |
| TGFbeta-IN-5; WAY-641966 | ||
| TGFβ-IN-5 is a TGFβ inhibitor useful for the study of fibroproliferative diseases associated with TGF-β signaling. | ||
| M30816 | Chlorphenesin carbamate | Others |
| Maolate; U 19646 | ||
| Chlorphenesin carbamate is a centrally acting skeletal muscle relaxant. Chlorphenesin carbamate can be used for the research of pain and discomfort related to skeletal muscle trauma and inflammation. Chlorphenesin carbamate is a selective blocker of polysynaptic pathways at the spinal and supra-spinal levels. Antinociceptive effect. | ||
| M56785 | AGN 196996 | RAR/RXR |
| AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM). | ||
| M57886 | A-119637 | Others |
| A-119637 | ||
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