About 1 result found for searched term "97682-44-5" (0.128 seconds)
Cat.No. | Name | Target |
---|---|---|
M4465 | Irinotecan | Topoisomerase |
(+)-Irinotecan; CPT-11; VAL-413 | ||
Irinotecan is an inhibitor of Topoisomerase I, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex. Irinotecan inhibits the growth of LoVo and HT-29 cells, with IC50s of 15.8 ± 5.1 and 5.17 ± 1.4 μM, respectively. |
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