About 3 results found for searched term "965-52-6" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2883 | Nifuroxazide | STAT |
| Nifuroxazide is a cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcription activity with IC50 of 3 μM against IL-6-induced STAT3 activation in U3A cells. | ||
| M21314 | LEO 39652 | PDE |
| LEO 39652 is a dual-soft PDE4 inhibitor with IC50 values of 1.2 nM for PDE4A, 1.2 nM for PDE4B, 3.0 nM for PDE4C, and 3.8 nM for PDE4D. LEO 39652 also inhibits TNF-α with an IC50 value of 6.0 nM. LEO 39652 is used in topical studies of atopic dermatitis. | ||
| M30862 | NSC49652 | Apoptosis |
| NSC49652 is a reversible, orally active p75 neurotrophin receptor (p75NTR, also known as NGFR, TNFRSF16, and CD271) inhibitor. NSC49652 targets the transmembrane domain of p75NTR. NSC49652 induces apoptosis and affects the viability of melanoma cells. | ||
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