About 3 results found for searched term "942-24-5" (0.117 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M16004 | Methyl 3-indolecarboxylate | Alkaloids |
| Methyl 3-indolecarboxylate | ||
| M3028 | Spironolactone | Mineralocorticoid Receptor |
| SC9420; Abbolactone | ||
| Spironolactone (SC9420) is an oral active aldosterone mineralocorticoid receptor antagonist with an IC50 value of 24 nM. Spironolactone is also an androgen receptor antagonist with an IC50 of 77 nM. Spironolactone promotes podocyte autophagy. | ||
| M29173 | GSK3494245 | Parasite |
| DDD01305143 | ||
| GSK3494245 (DDD01305143) is a potent, orally active, and selective inhibitor of the chymotrypsin-like activity of the parasite proteasome binding in a site sandwiched between the β4 and β5 subunits (IC50=0.16 μM for WT L. donovani proteasomes). GSK3494245 moderately inhibits chymotrypsin-like activity of human proteasome (IC50: purified 26S=13 µM; enriched THP-1 extracts IC50=40µM). GSK3494245 exhibits attractive biological and biosafety properties. | ||
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