About 2 results found for searched term "90-33-5" (0.089 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8392 | Tirapazamine | Apoptosis |
| SR259075; SR4233; Win59075; SML 0552; Tirazone; TPZ | ||
| Tirapazamine (TPZ,SR-4233, WIN 59075) is the first hypoxia-activated prodrug. Tirapazamine kills hypoxic cells by inducing chromosome aberrations and DNA double-strand breaks. Tirapazamine induced cell cycle arrest and apoptosis, and down-regulated HIF-1α, CA-IX and VEGF expression. | ||
| M9310 | 4-Methylumbelliferone | Others |
| Hymecromone, 4-MU | ||
| 4-methylumbelliferone is an inhibitor of hyaluronic acid (HA) synthesis, and 4Mu treatment leads to a 50% reduction in CD47mRNA levels with an IC50 value of 0.4mm in mouse models of liver cancer. | ||
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