About 10 results found for searched term "89-82-7" (0.052 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1792 | XL228 | IGF-1R |
| XL-228 | ||
| XL228 is a potent multikinase small-molecule inhibitor of insulin-like growth factor type 1 receptor (IGF1R). | ||
| M3483 | Flavopiridol hydrochloride | CDK |
| NSC 649890 HCl; Alvocidib hydrochloride; L86 8275 HCl; HMR-1275 HCl | ||
| Flavopiridol competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA. | ||
| M6065 | Ziprasidone HCl monohydrate | 5-HT Receptor |
| CP 88059 | ||
| Ziprasidone(CP88059) is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. | ||
| M9222 | LY3200882 | TGF-β Receptor |
| LY3200882 is a potent, highly selective, ATP-competitive and orally active TGF-β receptor type 1 (ALK5) inhibitor with an IC50 of 38.2 nM. LY3200882 is also used as an immune modulatory agent. | ||
| M9533 | DS-1001b (Safusidenib t-Butylamine) | Isocitrate Dehydrogenase (IDH) |
| Safusidenib | ||
| DS-1001b (Safusidenib t-Butylamine) is a potent, orally bioavailable, selective mutant IDH-1 (Isocitrate Dehydrogenase-1) inhibitor with antitumor activity. | ||
| M16046 | 8,8''-Biskoenigine | Alkaloids |
| 8,8''-Biskoenigine | ||
| M19357 | Menthone | TRP Channel |
| Pulegone is one of avian repellents. Pulegone stimulates both TRPM8 and TRPA1 channel in chicken sensory neurons and suppresses the former but not the latter at high concentrations. | ||
| M40070 | Odoratisol A | Others |
| Odoratisol A is found in Myristica fragrans. | ||
| M41115 | AcrB-IN-1 | Antibiotic |
| AcrB-IN-1 is a potent AcrB inhibitor. | ||
| M56953 | GPR132 antagonist 1 | Others |
| GPR132 antagonist 1 (GPR132-B-160, Compound 25) is a GPR132 antagonist with an EC50 value of 0.075 μM. | ||
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