About 6 results found for searched term "84-80-0" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1767 | R-406 | Syk |
| R406 free base | ||
| R406 is an orally bioavailable and selective inhibitor of spleen tyrosine kinase (Syk) with the IC50 of 41nM and Ki value of 30 nM. | ||
| M14420 | Vitamin K1 | Metabolite/Endogenous Metabolite |
| Phylloquinone; Phytomenadione | ||
| Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism. | ||
| M18901 | alpha-Arbutin | Others |
| alpha-Arbutin | ||
| M3802 | GF 109203X | PKC |
| GO 6850 | ||
| GF 109203X is a very potent and selective inhibitor of protein kinase C, selective for the α and β1 isoforms (IC50 values are 0.0084, 0.0180, 0.210, 0.132, and 5.8 μM for α, β1, δ, ε and ζ isoforms respectively). | ||
| M20715 | CS-2660 (JNJ-38158471) | VEGFR/PDGFR |
| CS-2660 (JNJ-38158471) is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with IC50 of 40 nM. CS-2660 (JNJ-38158471) also inhibits closely related tyrosine kinases such as Ret and Kit with IC50 of 180 nM and 500 nM，while it has no significant activity (>1 microM) against VEGFR-1 and VEGFR-3. | ||
| M30163 | SNAP 94847 | GPR/FFAR |
| SNAP 94847 is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with (Ki= 2.2 nM, Kd=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively. SNAP 94847 binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters. | ||
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