About 9 results found for searched term "80-75-1" (0.056 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1512 | Nimotuzumab | EGFR/HER2 |
| CAS# 780758-10-3 | ||
| Nimotuzumab (Nimotuzumab) is the first humanized monoclonal antibody targeting epidermal growth factor receptor (EGFR). Nimotuzumab has cytolytic effects on target tumors through its ability to induce antibody-dependent cell-mediated cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC). Nimotuzumab failed to recognize mouse EGFR. | ||
| M4038 | Astragaloside-I | Wnt/beta-catenin |
| Astrasieversianin IV; Cyclosieversioside B | ||
| Astragaloside I is a natural compound isolated from astragalus. Astragaloside I has osteogenic activity by stimulating osteoblast differentiation through the Wnt/β-catenin signaling pathway. | ||
| M4880 | Tulathromycin B | Antibiotic |
| RP17833 | ||
| M7693 | Chloro-APB hydrobromide | Dopamine Receptor |
| (±)-SKF 82958; Chloro-AP | ||
| Chloro-APB hydrobromide is a selective dopamine D1 receptor agonist and induces dopamine D1 receptor-dependent adenylate cyclase activity in rat striatal membranes (EC50=491 nM). | ||
| M8162 | SKF-83959 hydrobromide | Others |
| D1 dopamine receptor agonist. | ||
| M24611 | Simtuzumab | Monoamine Oxidase |
| AB 0024; GS 6624 | ||
| Simtuzumab (AB 0024; GS 6624) is a monoclonal antibody directed against Lysyl oxidase like-2 (LOXL2). Simtuzumab can be used for the research of primary sclerosing cholangitis (PSC). | ||
| M25224 | Cantuzumab mertansine | Drug-Linker Conjugates for ADC |
| SB-408075; huC242-DM1 | ||
| Cantuzumab mertansine (SB-408075; huC242-DM1), an ADC, is an immunoconjugate of the potent maytansine derivative and the humanized monoclonal antibody (huC242) directed to CanAg. Cantuzumab mertansine has cytotoxic toward colon cancer cells and has broad antitumor efficacy against a range of CanAg-positive human tumor xenografts. | ||
| M28898 | SIRT7 inhibitor 97491 | Sirtuin |
| SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.. | ||
| M42918 | 11alpha-Hydroxyprogesterone | Others |
| 11alpha-Hydroxyprogesterone is the inactive analogue of 11beta-Hydroxyprogesterone, and can be used as an experimental control. | ||
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