About 1 result found for searched term "8-CPT-2Me-cAMP sodium " (0.119 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M30401 | 8-CPT-2Me-cAMP sodium | Ras |
| 8-CPT-2Me-cAMP sodium is a selective activator of exchange proteins activated by cAMP (Epac), the cAMP sensitive guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-CPT-2Me-cAMP sodium activates Epac1 (EC50 = 2.2 μM), but not PKA (EC50> 10 μM). 8-CPT-2Me-cAMP sodium stimulates Epac-mediated Ca2+ release in pancreatic β-cells in vitro. | ||
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