About 3 results found for searched term "721-50-6" (0.135 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5897 | Prilocaine | Animal experimental anesthetics |
| NSC 40027 | ||
| Prilocaine is a local anesthetic of the amino amide type. It acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. | ||
| M1987 | LY2886721 | BACE |
| LY2886721 is an effective, selective, orally active inhibitor of beta-site amyloid precursor protein lyase 1 (BACE1) with an IC50 of 20.3 nM against recombinant human BACE1. LY2886721 showed higher selectivity for BACE1 than cathepsin D, pepsin and renin, but lacked selectivity for BACE2 (IC50 was 10.2 nM). LY2886721 crosses the blood-brain barrier and can be used to study Alzheimer's disease. | ||
| M30907 | B-Raf IN 11 | Raf |
| B-Raf IN 11 (ZINC72115182) is a selective B-RafV600E inhibitor (IC50=76 nM), shows selectivity for B-RafV600E over B-RafWT with selectivity of 3.1-fold. B-Raf IN 11 can be used in colorectal cancer research[1] | ||
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