About 8 results found for searched term "67-48-1" (0.278 seconds)
Cat.No. | Name | Target |
---|---|---|
M2517 | Choline Chloride | AChR/AChE |
Choline chloride is a quaternary ammonium salt used as an additive for animal feed. | ||
M9745 | DIDS sodium salt | VDAC |
MDL101114ZA | ||
DIDS sodium salt (MDL101114ZA) is a dual ABCA1 and VDAC1 inhibitor. DIDS sodium salt is also an anion transport inhibitor, which inhibits the ClC-Ka chloride channel and the bacterial ClC-ec1Cl-/H+ exchanger with IC50s of 100 μM and ~300 μM, respectively. | ||
M10712 | BIO-013077-01 | TGF-beta/Smad |
BIO-013077-01 is a Pyrazole inhibitor of TGF-β. | ||
M17043 | 2-(4-Hydroxyphenyl)-6-methyl- 2,3-dihydro-4H-pyran-4-one | Phenols |
2-(4-Hydroxyphenyl)-6-methyl- 2,3-dihydro-4H-pyran-4-one | ||
M8469 | Ro 67-4853 | Others |
Ro67-4853 is a positive allosteric modulator of metabotropic glutamate 1 (mGlu1) receptors. | ||
M20833 | Vodobatinib (K0706) | Src-bcr-Abl |
SCO-088, SUN K706, SUN-K0706 | ||
Vodobatinib (K0706, SCO-088, SUN K706, SUN-K0706) is a novel BCR-ABL1 tyrosine kinase inhibitor with an IC50 of 7 nM. Vodobatinib exhibits activity against most BCR-ABL1 point mutants with IC50s of 167 nM, 154 nM,165 nM and 1967 nM for BCR-ABL1L248R, BCR-ABL1Y253H , BCR-ABL1E255V and BCR-ABL1T315I, respectively. | ||
M28479 | VU0467485 | AChR/AChE |
AZ13713945 | ||
VU0467485 (AZ13713945) is a potent, selective, and orally bioavailable muscarinic acetylcholine receptor 4 (M4) positive allosteric modulator (PAM). VU0467485 (AZ13713945) potentiates activity of ACh at M4 with EC50s of 26.6 nM and 78.8 nM at rat and human M4 receptors, respectively. VU0467485 (AZ13713945) shows selectivity for M4 over human and rat M1/2/3/5. VU0467485 (AZ13713945) displays moderate to high CNS penetration. VU0467485 (AZ13713945) has antipsychotic-like activity. | ||
M28634 | PF-06648671 | Gamma-secretase/Beta-secretase |
PF-06648671 is a novel, brain-penetrable, and orally active γ-secretase modulator (GSM). PF-06648671 reduces Aβ42 and Aβ40, with concomitant increases in Aβ37 and Aβ38 in vitro. PF-06648671 is used for the study of Alzheimer’s disease. |
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