About 1 result found for searched term "667463-82-3" (0.177 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M20836 | Indirubin-3′-oxime | GSK-3 |
| IDR3O, I3O | ||
| Indirubin-3′-oxime (IDR3O, I3O) is an indirubin analogue that shows favorable inhibitory activity targeting GSK-3β and CDKs. Indirubin-3′-oxime also inhibits JNKs with IC50s of 0.8 μM, 1.4 μM, and 1.0 μM for JNK1, JNK2, and JNK3, respectively. Indirubin-3′-oxime activates Wnt/β-catenin signaling and inhibits adipocyte differentiation and obesity. | ||
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