About 3 results found for searched term "518-82-1" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7790 | Emodin | Casein Kinase |
| Frangula emodin | ||
| Emodin is an anti-SARS-CoV compound that blocks the interaction between the SARS-coronavirus spike protein and angiotensin converting enzyme 2 (ACE2). Emodin inhibited casein kinase 2 (CK2) and 11β-HSD1. Emodin can also induce necrotic apoptosis of glioma U251 cells and inhibit U251 cell proliferation by targeting the TNF/RIPK1/RIPK3 signaling pathway. | ||
| M10259 | Spastazoline | Others |
| Spastazoline is a potent and selective, cell permeable inhibitor for aaa+ (atpases associated with diverse cellular activities) proteins, inhibiting the microtubule-severing aaa+ protein spastin, with IC50 of 99 nM for human spastin. | ||
| M20777 | GSK5182 | Estrogen Receptor |
| GSK5182 is a 4-Hydroxytamoxifen analog and a highly potent, selective, orally active estrogen-related receptor gamma (ERRγ) inverse agonist with an IC50 value of 79 nM.GSK5182 does not interact with other nuclear receptors, including ERRα and ERα. In addition, GSK5182 inhibits proinflammatory cytokine-induced catabolic factors and increases ROS production in liver cancer cells. cytokine-induced catabolic factors and increased ROS production in hepatocellular carcinoma cells. | ||
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