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 About 10 results found for searched term "51-21-8" (0.052 seconds)

Cat.No.  Name Target
M1937 Dapagliflozin SGLT
BMS-512148
Dapagliflozin (BMS-512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2).
M2289 5-fluorouracil DNA/RNA Synthesis
5-FU, Carac, Efudex; Adrucil
5-fluorouracil (5-FU) is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools.
M2712 Fosaprepitant dimeglumine salt Neurokinin Receptor
MK-0517 dimeglumine salt; L-758,298 dimeglumine salt
Fosaprepitant is a water-soluble phosphoryl procompound for Aprepitant which is a NK1 antagonist.*The compound is unstable in solutions, freshly prepared is recommended
M5551 Dapagliflozin ((2S)-1,2-propanediol, hydrate) SGLT
BMS-512148 (2S)-1,2-propanediol, hydrate
Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the S-enantiomer of Dapagliflozin 1,2-propanediol, hydrate.
M13923 CCR2-RA-[R] CCR
CCR2-RA-[R] is an allosteric antagonist of the C-C chemokine receptor type 2 (CCR2) with an IC50 of 103 nM.
M21025 Balofloxacin Dihydrate PPAR
an agonist of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway
M21427 CB1 agonist 1 Cannabinoid
CB1 agonist 1 is an agonist of CB1. The pIC50 value of CB1 agonist 1 affinity with CB1 receptor was 5.7. CB1 agonist 1 can be used in the study of brain disorders.
M29522 dMCL1-2  PROTAC
dMCL1-2 is a potent and selective PROTAC of myeloid cell leukemia 1 (MCL1) (Bcl-2 family member) based on Cereblon, which binds to MCL1 with a KD of 30 nM. dMCL1-2 activats the cellular apoptosis machinery by degradation of MCL1.
M30213 AR03 DNA/RNA Synthesis
BMH-23
AR03 (BMH-23) is an apurinic/apyrimidinic endonuclease 1 (Ape1) inhibitor with an IC50 of 2.1 µM. AR03 has low affinity for double-stranded DNA. AR03 potentiates the cytotoxicity of methyl methanesulfonate and temozolomide in SF767 cells.
M38915 Vanicoside B CDK
Vanicoside B targets cyclin-dependent kinase 8 (CDK8) and exhibits anti-tumor activity. The potential mechanism is Vanicoside B blocks CDK8-mediated signaling pathways and decreases the expression of epithelial-mesenchymal transition proteins, so that it leads to cell cycle arrest and apoptosis.



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