About 12 results found for searched term "51-21-8" (0.053 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1937 | Dapagliflozin | SGLT |
| BMS-512148 | ||
| Dapagliflozin (BMS-512148) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2). | ||
| M2289 | 5-Fluorouracil | DNA/RNA Synthesis |
| 5-FU, Carac, Efudex; Adrucil | ||
| 5-Fluorouracil (5-FU) is a potent antitumor agent that affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. | ||
| M2712 | Fosaprepitant dimeglumine salt | Neurokinin Receptor |
| MK-0517 dimeglumine salt; L-758,298 dimeglumine salt | ||
| Fosaprepitant is a water-soluble phosphoryl procompound for Aprepitant which is a NK1 antagonist.*The compound is unstable in solutions, freshly prepared is recommended | ||
| M5551 | Dapagliflozin ((2S)-1,2-propanediol, hydrate) | SGLT |
| BMS-512148 (2S)-1,2-propanediol, hydrate | ||
| Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the S-enantiomer of Dapagliflozin 1,2-propanediol, hydrate. | ||
| M13923 | CCR2-RA-[R] | CCR |
| CCR2-RA-[R] is an allosteric antagonist of the C-C chemokine receptor type 2 (CCR2) with an IC50 of 103 nM. | ||
| M21025 | Balofloxacin Dihydrate | PPAR |
| an agonist of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway | ||
| M21427 | CB1 agonist 1 | Cannabinoid |
| CB1 agonist 1 is an agonist of CB1. The pIC50 value of CB1 agonist 1 affinity with CB1 receptor was 5.7. CB1 agonist 1 can be used in the study of brain disorders. | ||
| M29522 | dMCL1-2 | PROTAC |
| dMCL1-2 is a potent and selective PROTAC of myeloid cell leukemia 1 (MCL1) (Bcl-2 family member) based on Cereblon, which binds to MCL1 with a KD of 30 nM. dMCL1-2 activats the cellular apoptosis machinery by degradation of MCL1. | ||
| M30213 | AR03 | DNA/RNA Synthesis |
| BMH-23 | ||
| AR03 (BMH-23) is an apurinic/apyrimidinic endonuclease 1 (Ape1) inhibitor with an IC50 of 2.1 µM. AR03 has low affinity for double-stranded DNA. AR03 potentiates the cytotoxicity of methyl methanesulfonate and temozolomide in SF767 cells. | ||
| M38915 | Vanicoside B | CDK |
| Vanicoside B targets cyclin-dependent kinase 8 (CDK8) and exhibits anti-tumor activity. The potential mechanism is Vanicoside B blocks CDK8-mediated signaling pathways and decreases the expression of epithelial-mesenchymal transition proteins, so that it leads to cell cycle arrest and apoptosis. | ||
| M57690 | 8-Hydroxy-PIPAT oxalate | Others |
| 8-Hydroxy-PIPAT oxalate | ||
| M57934 | Ar-BINMOL-3 | Others |
| Ar-BINMOL-3 | ||
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