About 6 results found for searched term "50-65-7" (0.054 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1671 | BEZ235 | PI3K |
| NVP-BEZ235, Dactolisib | ||
| BEZ235 (NVP-BEZ235) is a potent dual PI3K and mTOR inhibitor of p110α, p110γ, p110δ and p110β with IC50 of 4 nM, 5 nM, 7 nM and 75 nM, respectively. | ||
| M2055 | Niclosamide | STAT |
| Niclocide | ||
| Niclosamide is an inhibitor of STAT3 with an IC50 value of 0.25 μM. | ||
| M5027 | CPI-169 racemate | EZH2 |
| CPI-169 racemate is the racemate form of CPI-169, which is a novel and potent EZH2 inhibitor with IC50 <1 nM(inhibition of the catalytic activity of PRC2); decreases cellular levels of H3K27me3 with an EC50 of 70 nM, and triggers cell cycle arrest and apoptosis in a variety of cell lines. | ||
| M11024 | ROCK2-IN-2 | ROCK |
| Rock2-in-2 is a selective ROCK2 inhibitor with IC50 <1 μM. | ||
| M11238 | UNC569 | TAM Receptor |
| UNC569 is a potent, reversible, ATP-competitive and orally active Mer kinase inhibitor with IC50 of 2.9 nM and Ki of 4.3 nM. UNC569 also inhibited Axl and Tyro3 with IC50 of 37 nM and 48 nM, respectively. | ||
| M38799 | Niranthin | Parasite |
| Niranthin, a lignan with a wide spectrum of pharmacological activities. Niranthin is a potent and non-competitive inhibitor of heterodimeric type IB topoisomerase of L. donovani. Niranthin can be used for the research of drug-resistant leishmaniasis research. | ||
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