About 9 results found for searched term "50-22-6" (0.052 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4241 | Shikonofuran-A | Others |
| Shikonofuran A is A natural product isolated from the roots of Lithosperraum erythrorhizon Sieb. | ||
| M5533 | Corticosterone | GCR |
| 17-Deoxycortisol; 11β,21-Dihydroxyprogesterone; Kendall's compound B | ||
| Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system. Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. | ||
| M11467 | GSK-2250665A | Itk |
| GSK2250665; GSK-2250665 | ||
| GSK-2250665A is a Itk inhibitor with pKi value of 9.2. | ||
| M25085 | Geptanolimab | PD-1/PD-L1 |
| APL-501; CBT-501; GB-226 | ||
| Geptanolimab (CBT-501) is a humanized IgG4k monoclonal antibody against programmed death-1 (PD-1). Siplizumab inhibits the binding of PD-L1/L2 to PD-1 through a competitive action. Siplizumab can be used in research of cancer. | ||
| M28592 | BMS-P5 free base | PAD |
| BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 free base blocks MM-induced NET formation and delays progression of MM in a syngeneic mouse model. | ||
| M29960 | SB 202190 hydrochloride | p38 MAPK |
| SB 202190 hydrochloride is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 hydrochloride binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 hydrochloride has anti-cancer activity. SB202190 hydrochloride induces autophagy. | ||
| M40388 | Gentiside B | Others |
| Gentiside B has neuritogenic activity and induce neurite outgrowth. Gentiside B can be isolated from the root and rhizome of Gentiana rigescens. Gentiana has hepatoprotective, anti-inflammatory, analgesic, antiproliferative and antimicrobial effects. | ||
| M45194 | L-Tryptophanamide hydrochloride | Metabolite/Endogenous Metabolite |
| H-Trp-NH2.HCl | ||
| L-Tryptophanamide hydrochloride is an endogenous metabolite. | ||
| M56007 | DPQ hydrochloride | PARP |
| DPQ hydrochloride (6, 7-dimethoxy-2 -(1-piperazinyl)-4-quinazolinamine hydrochloride) is a PARP1 inhibitor, with IC50 value of 40 nM. | ||
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