About 10 results found for searched term "5-HT6 agonist 1" (0.159 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41748 | 5-HT6R antagonist 1 | 5-HT Receptor |
| 5-HT6R antagonist 1 is a 5-HT6R antagonist (Ki: 5 nM). | ||
| M41754 | 5-HT6 agonist 1 | 5-HT Receptor |
| 5-HT6 agonist 1 is a 5-HT6 agonist (Ki: 5 nM). | ||
| M3000 | Intepirdine | 5-HT Receptor |
| GSK 742457; SB-742457; RVT-101 | ||
| Intepirdine (SB742457) is a highly selective 5-HT6 receptor antagonist with pKi of 9.63, exhibits >100-fold selectivity over other receptors. | ||
| M5134 | WAY-181187 | 5-HT Receptor |
| SAX-187 | ||
| Way-181187 (SAX-187) is an effective selective 5-HT6 receptor agonist with Ki of 2.2 nM and EC50 of 6.6 nM. WAY181187 mediates 5-HT6 receptor-dependent signaling pathways, such as cAMP, Fyn and ERK1/2 kinases, as specific agonists. | ||
| M9763 | AVN-492 | 5-HT Receptor |
| AVN-492 is a potent and selective 5-HT6R antagonist, binds to 5-HT6R (Ki = 91 pM). | ||
| M28859 | Masupirdine mesylate | 5-HT Receptor |
| SUVN-502 mesylate | ||
| Masupirdine mesylate (SUVN-502 mesylate) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist (Ki of 2.04 nM for human 5-HT6 receptor). Masupirdine mesylate (SUVN-502 mesylate) shows high selectivity over 5-HT2A receptor and other 100 target sites, and has potential for treatment of Alzheimer's disease. | ||
| M29342 | SB357134 | 5-HT Receptor |
| SB-357134 is a potent, selective, brain penetrant, and orally active 5-HT6 receptor antagonist. SB-357134 enhances memory and learning and increases seizure threshold in rats. | ||
| M30514 | Masupirdine free base | 5-HT Receptor |
| SUVN-502 free base | ||
| Masupirdine free base (SUVN-502 free base) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist (Ki of 2.04 nM for human 5-HT6 receptor). Masupirdine free base (SUVN-502 free base) shows high selectivity over 5-HT2A receptor and other 100 target sites, and has potential for treatment of Alzheimer's disease. | ||
| M30848 | PRX-07034 hydrochloride | 5-HT Receptor |
| PRX-07034 hydrochloride is a highly selective and potent 5-HT6 receptor antagonist with a Ki= 4-8 nM and an IC50 of 19 nM. PRX-07034 can be used for the research of enhancing working memory and cognitive flexibility. | ||
| M56096 | BGC20-761 | 5-HT Receptor |
| BGC20-761 is a selecvtive 5-HT6 and dopamine receptor antagonist (human receptor Ki values: 5-HT6 (20 nM), 5-HT2A (69 nM), D2 (140 nM). | ||
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