About 1 result found for searched term "2523017-04-9" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29690 | SK-575-NEG | PARP |
| SK-575-NEG (compound 28), a methylation counterpart of SK-575, is synthesized by methylation of the amino group of piperidine-2,6-dione in SK-575 as an control compound. SK-575-NEG is strongly bound to PARP1, with an IC50 of 2.64 nM. SK-575-NEG was completely ineffective in inducing PARP1 degradation in MDA-MB-436 and Capan-1 cells at concentrations up to 1 μM. | ||
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