About 2 results found for searched term "25-Hydroxycholesterol" (0.552 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9313 | 25-Hydroxycholesterol | Metabolite/Endogenous Metabolite |
| 25-OHC | ||
| 25-Hydroxycholesterol is a cholesterol metabolite produced and secreted by macrophages in response to toll-like receptor (TLR) activation. 25-Hydroxycholesterol effectively and selectively inhibited IgA production in B cells with EC50 of about 65 nM. | ||
| M30428 | 7α,25-Dihydroxycholesterol | GPR/FFAR |
| 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC50=140 pM; Kd=450 pM). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells. | ||
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