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 About 1 result found for searched term "2375840-87-0" (0.42 seconds)

Cat.No.  Name Target
M9587 NDI-091143 ATPase
NDI-091143 is a novel potent inhibitor of human ATP-citrate lyase with an IC50 of 2.1 nM (ADP-Glo assay), a Ki of 7.0 nM and a Kd of 2.2 nM. NDI-091143 inhibits ACLY catalysis allosterically, by stabilizing large conformational changes in the citrate domain that indirectly block the binding and recognition of citrate.



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