About 1 result found for searched term "2245887-38-9" (0.648 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29426 | DI-591 | E1/E2/E3 Enzyme |
| DI-591 is a potent, high-affinity and cell-permeable inhibitor of the DCN1-UBC12 interaction. DI-591 binds to DCN1 and DCN2 with Ki values of 12 nM and 10.4 nM, respectively and has no appreciable binding to DCN3, DCN4, and DCN5 proteins. DI-591 selectively inhibits neddylation of cullin 3 but has no or minimal effect on neddylation of other cullin family members. | ||
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