About 1 result found for searched term "2230854-93-8" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29392 | ARN-21934 | Topoisomerase |
| ARN-21934 is a potent, highly selective, blood-brain barrier (BBB) penetrant inhibitor for human topoisomerase II α over β. ARN-21934 inhibits DNA relaxation with an IC50 of 2 μM as compared to the anticancer agent Etoposide (IC50=120 μM). ARN-21934 exhibits a favorable in vivo pharmacokinetic profile and is a promising lead compound for anticancer research. | ||
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