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 About 1 result found for searched term "219639-75-5" (0.133 seconds)

Cat.No.  Name Target
M20998 PMX-53 Complement System
3D53; PMX53; Ac-Phe-[Orn-Pro-dCha-Trp-Arg]
PMX-53 is a potent CD88 (C5aR) antagonist with an IC50 of 20 nM, it inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also a low-affinity MrgX2 agonist that stimulates MrgX2-mediated mast cell degranulation.



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