About 1 result found for searched term "1978336-61-6" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9897 | GB1107 | Galectin |
| GB-1107 | ||
| GB1107 is a potent, selective, orally active galectin-3 inhibitor with Kd of 37 nM. GB1107 inhibits lung adenocarcinoma growth and augments response to PD-L1 blockade. GB1107 potentiates the effects of a PD-L1 immune checkpoint inhibitor to increase expression of cytotoxic (IFN-γ, granzyme B, perforin-1, Fas ligand) and apoptotic (cleaved caspase-3) effector molecules. | ||
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