About 5 results found for searched term "121-75-5" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M14549 | Malathion | AChR/AChE |
| Malathion is an organophosphate parasympathomimetic which binds irreversibly to cholinesterase, is an insecticide of relatively low human toxicity. | ||
| M42626 | Aβ/tau aggregation-IN-3 | Amyloid |
| Aβ/tau aggregation-IN-3 is a potent amyloid protein aggregation inhibitor with an IC50 of 0.85 μM by Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay. | ||
| M2042 | Cilengitide | Integrin |
| EMD 121974, NSC 707544 | ||
| Cilengitide (EMD 121974, NSC 707544) is a selective inhibitor of αvβ3 integrin and αvβ5 integrin with IC50 of 1 nM and 140 nM, respectively. | ||
| M28961 | TH1217 | Anti-infection |
| ZINC1775962367 | ||
| TH1217 (ZINC1775962367) is a potent and selective dCTPase pyrophosphatase 1 (dCTPase) inhibitor, with an IC50 of 47 nM. TH1217 enhances the cytotoxic effect of cytidine analogues in leukemia cells. TH1217 also could modulate SARS-Cov-2 interactors, so it shows activity of against COVID-19. | ||
| M29045 | R121919 | CRFR |
| NBI30775 | ||
| R121919 (NBI30775) is a potent small-molecule CRF1 receptor antagonist with a Ki of 2 to 5 nM for the CRF1 receptor and over 1000-fold weaker activity at the CRF2 receptor, CRF-binding protein, or 70 other receptor types. | ||
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