About 1 result found for searched term "1184843-57-9" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M11418 | SAR-020106 | Checkpoint |
| Sar-020106 is an ATP-competitive and selective CHK1 inhibitor with an IC50 of 13.3 nM. Sar-020106 has good selectivity to CHK2. Sar-020106 increased cell lethality of Gemcitabine and SN38 by 3.0 to 29 times in a p53-dependent manner in several colon cancer cell lines. Sar-020106 can enhance antitumor activity by selecting anticancer drugs. | ||
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