About 6 results found for searched term "( )-SHIN1" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M14768 | (+)-SHIN1 | Others |
| (+)-RZ-2994 | ||
| (+)-SHIN1 ((+)-RZ-2994) is an active (+) enantiomer of SHIN1. | ||
| M14769 | (-)-SHIN1 | Others |
| (-)-RZ-2994 | ||
| (-)-SHIN1 ((-)-RZ-2994) is an inactive (−) enantiomer of SHIN1. | ||
| M29345 | (Rac)-SHIN2 | Others |
| (Rac)-SHIN2 is a serine hydroxymethyltransferase (SHMT) inhibitor having 1,4-dihydropyrano[2,3-c]pyrazole structure. (Rac)-SHIN2 involves in folate or one-carbon metabolism pathways, prevents viral infection. SHMT1 and SHMT2 are the cytosolic and/or mitochondrial isoforms of serine hydroxymethyltransferase, respectively. | ||
| M30600 | 1,2-Dihydrotanshinone | Others |
| 1,2-Dihydrotanshinquinone | ||
| 1,2-Dihydrotanshinone (1,2-Dihydrotanshinquinone) is an abietane diterpene. 1,2-Dihydrotanshinone inhibits the formation of the pathogenic complex formed between (CUG)n-RNA and the splicing-factor muscleblind-like 1 (MBNL1). 1,2-Dihydrotanshinone can be used for the research of myotonic dystrophy type 1. | ||
| M38950 | Tanshindiol C | Histone Methyltransferase |
| Tanshindiol C is a S-adenosylmethionine-competitive EZH2 (Histone Methyltransferase) inhibitor with an IC50 of 0.55 μM for inhibiting the methyltransferase activity. Tanshindiol C is also an activator of both Nrf2 and Sirtuin 1 (Sirt1) in macrophages. | ||
| M39188 | Deoxyneocryptotanshinone | BACE |
| Deoxyneocryptotanshinone is a high affinity BACE1 (Beta-secretase) inhibitor with an IC50 value of 11.53 μM. Deoxyneocryptotanshinone shows a promising dose-dependent inhibition of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 133.5 μM. | ||
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