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Zopolrestat is an inhibitor of Aldose Reductase. AR family members AKR1B1 and AKR1B10 have additionally been shown to play roles in inflammation and cancer.
| Molecular Weight | 419.38 |
| Formula | C19H12F3N3O3S |
| CAS Number | 110703-94-1 |
| Solubility (25°C) | DMSO: ≥20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Ghada Bouguerra, et al. Zopolrestat Induced Suicidal Death of Human Erythrocytes
[3] Jing Zhai, et al. Zopolrestat as a human glyoxalase I inhibitor and its structural basis
[5] P B Inskeep, et al. Pharmacokinetics of the aldose reductase inhibitor, zopolrestat, in humans
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