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Ziresovir

Cat. No. M28390

All AbMole products are for research use only, cannot be used for human consumption.

Ziresovir Structure
Synonym:

AK0529; RO-0529

Price and Availability

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Quality Control & Documentation
Biological Activity

Ziresovir (AK0529;RO-0529) is a potent, selective, and orally bioavailable respiratory syncytial virus (RSV) fusion (F) protein (RSV F) protein inhibitor. Ziresovir shows anti-RSV activity (EC50=3 nM) and highlights pharmacokinetics in animal species.

Chemical Information
Molecular Weight 439.53
Formula C22H25N5O3S
CAS Number 1422500-60-4
Form Solid
Solubility (25°C) DMSO 125 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yuzhen Gao, et al. Molecules. Evaluation of Small Molecule Combinations against Respiratory Syncytial Virus In Vitro

[2] Xiufang Zheng, et al. J Med Chem. Discovery of Ziresovir as a Potent, Selective, and Orally Bioavailable Respiratory Syncytial Virus Fusion Protein Inhibitor

[3] John H Beigel, et al. Antiviral Res. Advances in respiratory virus therapeutics - A meeting report from the 6th isirv Antiviral Group conference

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Keywords: Ziresovir, AK0529; RO-0529 supplier, RSV, inhibitors, activators

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