About 7 results found for searched term "RSV" (0.055 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8623 | RSV604 (A-60444) | RSV |
| A-60444; RSV-604 | ||
| RSV604 (A-60444) is a cell-permeable, non-cytotoxic (CC50 >50 μM) benzodiazepine derivative that is reported to target respiratory syncytial virus (RSV) nucleoprotein (N), with a Kd of 1.6 μM. RSV604 displays submicromolar activity against numerous clinical isolates of both the A and B subtypes of RSV (average EC50s=0.8 μM). | ||
| M31204 | RSVA405 | AMPK |
| RSVA405 is a potent, orally active activator of AMPK, with an EC50 of 1 μM. RSVA405 facilitates CaMKKβ-dependent activation of AMPK, inhibits mTOR, and promotes autophagy to increase Aβ degradation. RSVA405 has anti-inflammatory effects through the inhibition of STAT3 function. | ||
| M41245 | RSV L-protein-IN-3 | RSV |
| RSV L-protein-IN-3 is a wild-type RSV polymerase inhibitor with an IC50 value of 10.4 μM and an EC50 value of 2.1 μM (against RSV). | ||
| M41247 | RSV L-protein-IN-1 | RSV |
| RSV L-protein-IN-1 is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.021 μM). | ||
| M41248 | RSV L-protein-IN-5 | RSV |
| RSV L-protein-IN-5 is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.1 μM). | ||
| M41249 | RSV L-protein-IN-4 | RSV |
| RSV L-protein-IN-4 is a noncompetitive RSV polymerase inhibitor (IC50: 0.88 μM). | ||
| M41250 | RSV L-protein-IN-2 | RSV |
| RSV L-protein-IN-2 is a noncompetitive RSV polymerase inhibitor (IC50: 4.5 μM). | ||
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