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Presatovir

Cat. No. M5048

All AbMole products are for research use only, cannot be used for human consumption.

Presatovir Structure
Synonym:

GS-5806

Size Price Availability Quantity
1mg USD 110  USD110 In stock
5mg USD 280  USD280 In stock
10mg USD 420  USD420 In stock
25mg USD 740  USD740 In stock
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Quality Control & Documentation
Biological Activity

Presatovir is a novel, orally bioavailable RSV fusion inhibitor discovered following a lead optimization campaign on a hit originated from a phenotypic RSV antiviral high-throughput screen. Presatovir exhibits potent activity against a wide range of RSV A and B clinical isolates.Presatovir demonstrates dose-dependent (0-30 mg/kg) antiviral efficacy in a cotton rat model of RSV infection.

Chemical Information
Molecular Weight 532.06
Formula C24H30ClN7O3S
CAS Number 1353625-73-6
Solubility (25°C) 10 mM in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mackman RL,et.al. J Med Chem. Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study.

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Keywords: Presatovir, GS-5806 supplier, RSV, inhibitors, activators

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