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Zanolimumab

Cat. No. M25242

All AbMole products are for research use only, cannot be used for human consumption.

Zanolimumab Structure
Synonym:

Anti-Human CD4 Recombinant Antibody

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Quality Control & Documentation
Biological Activity

Zanolimumab (Anti-Human CD4 Recombinant Antibody) is a fully human monoclonal antibody targets CD4. Zanolimumab effectively inhibits T-cell receptor (TCR) signal transduction. Zanolimumab can be used for the research of heumatoid arthritis, psoriasis, melanoma, cutaneous and peripheral T-cell lymphoma.

Chemical Information
CAS Number 652153-01-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Anton B Alexandroff, et al. Br J Haematol. Alemtuzumab-resistant Sézary syndrome responding to zanolimumab

[2] Francesco d'Amore, et al. Br J Haematol. Phase II trial of zanolimumab (HuMax-CD4) in relapsed or refractory non-cutaneous peripheral T cell lymphoma

[3] Dominik Sebastian Mestel, et al. Expert Opin Biol Ther. Zanolimumab, a human monoclonal antibody targeting CD4 in the treatment of mycosis fungoides and Sézary syndrome

[4] Youn H Kim, et al. Blood. Clinical efficacy of zanolimumab (HuMax-CD4): two phase 2 studies in refractory cutaneous T-cell lymphoma

[5] L S Villadsen, et al. Arch Dermatol Res. In situ depletion of CD4+ T cells in human skin by Zanolimumab

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Keywords: Zanolimumab, Anti-Human CD4 Recombinant Antibody supplier, inhibitors, activators

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