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YM 022

Cat. No. M7501

All AbMole products are for research use only, cannot be used for human consumption.

YM 022 Structure

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Quality Control & Documentation
Biological Activity

YM 022 is a extremely potent and highly selective non-peptide CCK2 silent antagonist (Ki values are 68 pM and 63 nM at CCK2 and CCK1 receptors respectively). Acts in vivo to potently inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation with a long duration of action.

Chemical Information
Molecular Weight 516.6
Formula C32H28N4O3
CAS Number 145084-28-2
Solubility (25°C) DMSO 51.66 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bromidge, et al. J Med Chem. 5-Chloro-N-(4-methoxy-3-piperazin-1-yl-phenyl)-3-methyl-2-benzothiophenesulfonamide (SB-271046): a potent, selective, and orally bioavailable 5-HT6 receptor antagonist.

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Abmole Inhibitor Catalog




Keywords: YM 022 supplier, inhibitors, activators

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