XL019

Cat. No. M2566

All AbMole products are for research use only, cannot be used for human consumption.

Size	Price	Availability
10mM*1mL in DMSO	USD 94 USD94	In stock
5mg	USD 85 USD85	In stock
10mg	USD 135 USD135	In stock
50mg	USD 470 USD470	In stock

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XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, exhibiting >50-fold selectivity over JAK1, JAK3 and TYK2.

	Source	Anticancer Res (2017). Figure 2. XL019
	Method	fluorescence-activated cell sorting analyses
	Cell Lines	KBV20C cancer cells
	Concentrations	5 μM
	Incubation Time	24 h
	Results	As shown in Figure 2A, co-treatment with XL019 and vincristine increased the number of cells arrested in the G2 phase compared to that observed with single treatments with either agent.

Molecular Weight	444.53
Formula	C25H28N6O2
CAS Number	945755-56-6
Solubility (25°C)	DMSO 15 mg/mL
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

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