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WAY 181187 oxalate

Cat. No. M7482

All AbMole products are for research use only, cannot be used for human consumption.

WAY 181187 oxalate Structure

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Biological Activity

WAY 181187 oxalate is a high affinity and selective 5-HT6 agonist (Ki = 2.2 nM). Displays 60-fold selectivity over other 5-HT and monoamine receptors. Increases firing rate of 5-HT neurons. Modifies sleep and wakefulness profiles following direct injections into the dorsal raphe nucleus, in vivo. Orally bioavailable.

Chemical Information
Molecular Weight 470.91
Formula C15H13ClN4O2S2.C2H2O4
CAS Number 1883548-85-3
Solubility (25°C) DMSO 47.09 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Brown, et al. J Neurochem. [3H]-Homoquinolinate binds to a subpopulation of NMDA receptors and to a novel binding site.

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