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VU 1545

Cat. No. M7477

All AbMole products are for research use only, cannot be used for human consumption.

VU 1545 Structure

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Quality Control & Documentation
Biological Activity

VU 1545 is a metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulator (EC50 = 9.6 nM, Ki = 156 nM at rat mGlu5).

Chemical Information
Molecular Weight 402.38
Formula C22H15FN4O3
CAS Number 890764-63-3
Solubility (25°C) DMSO 40.24 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Matuszek, et al. Eur J Pharmacol. An investigation of tachykinin NK2 receptor subtypes in the rat.

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